TRALULALA

Tracheomalacia in Focus

Overview

Understanding Lung Disease in Children with Esophageal Atresia and Tracheomalacia

Tralulala is a national Danish research project focused on understanding respiratory complications in children born with esophageal atresia (EA) – a rare congenital malformation often accompanied by tracheomalacia (TM).

While survival and surgical outcomes have improved significantly in recent decades, many children experience long-term respiratory symptoms such as wheezing, coughing, and exercise intolerance. However, respiratory disease remains understudied in this population.

We aim to:

  • Describe the burden of respiratory disease

  • Improve our understanding of the underlying airway abnormalities

  • Develop better tools for diagnosis and follow-up

  • Guide future treatment strategies and clinical care


📅 Timeline (short version)

Year Activity
2023 Register study and pilot study initiated
2024 Pilot study completed
2025 National cross-sectional study launched
2026–2027 Data collection and analysis
2027–2028 Biomarker study and long-term follow-up


(C) 2023 Marika Rønne, marika.nathalie.roenne@regionh.dk

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